Filtration using a Buchner funnel Essay Filtration using a Buchner funnel Essay Acetophenetidin can be formed through two methods, Williamson ether synthesis and amide synthesis. By working in groups of two we were able to complete both methods of synthesis routes. The end result should be the synthesis of a similar product, by verification between the two individuals.
Synthesis of Acetophenetidin by Amide Synthesis Essay Synthesis of Acetophenetidin by Amide Synthesis Essay The goals of this experiment are to determine if the products derived from amide synthesis and Williamson Ether Synthesis are identical, and if one of the synthetic routes is more advantageous than the other.
In Part 1, an attempt to synthesize acteophenetidin crystals by amide synthesis was made. We began by removing the colored impurities from the p-Phenetidine reddish-brown by placing 2g of the sample in 38 mL of hydrochloric acid and heating the solution to boiling point.
Upon reaching just below boiling point, decolorizing carbon was added to the solution, and the solution was allowed cooled for minutes. Then, 9 mL of sodium acetate buffer, to maintain a relatively constant pH and 1.
Then, to induce crystallization, the beaker was placed in an ice bath.
The slightly white, powdery crystals were collected using the Buchner funnel, and allowed to dry in the funnel and then on a watch glass. The mass of the crude sample collected was 2.
I believe that the mass of the crude sample was inaccurate due to liquid remaining in the sample of crystals after drying. The measured melting point of the crude sample was C — Related posts:.Mechanism of amide synthesis of acetophenetidin Mechanism of Williamson ether synthesis of acetophenetidin How do these synthesis apply principles of green chemistry, and %(1).
Between amide synthesis of acetophenetidin and Williamson ether synthesis of acetophenetidin, is one procedure "greener" than the other?
Explain your reasoning. Synthesis of acetophenetidin by Williamson Ether synthesis produced purer crystals, but amide synthesis produced a larger crude mass (greener pathway). Recrystallizing the crude product formed from amide synthesis gave purer crystals that were identical to .
Acetophenetidin can be formed through two methods, Williamson ether synthesis and amide synthesis. By working in groups of two we were able to complete both methods of synthesis routes. The end result should be the synthesis of a similar product, by verification between the two individuals.
Calculate the theoretical yield in grams for the amide synthesis (not Williamson ether synthesis) of phenacetin.
The density of p- phenetidine is g/mL, and the given mass is g. We are also given mL of acetic anhydride as a starting material (molar mass g/mol)%(4). what is the purpose of the sodium acetate solution in the amide synthesis of acetophenetidin?
sodium acetate acts as a buffer, maintaining ph at a good level for the reaction, and to act as a solvent.